Robert Lewandowski could make Champions League history on Wednesday, and Real Madrid will try to avoid the rarity of three losses in a row.
After starring to begin the season, Zlatan Ibrahimovic could renew his deal at Milan.
Bouna Sarr has followed Douglas Costa and Eric Maxim Choupo-Moting in joining Bundesliga champions Bayern Munich on Monday.
Paris Saint-Germain Neymar and Marseille defender Alvaro have both avoided sanctions for alledged racist abuse during Le Classique.
Paris Saint-Germain will have Neymar back for the visit to Reims after he completed his two-game suspension.
Angel Di Maria will miss four Ligue 1 matches after the Argentine was suspended for an incident involving Marseille's Alvaro.
One of five players sent off in Sunday's Classique, Paris Saint-Germain forward Neymar has been banned for two matches.
Neymar was sent off against Marseille and ex-winger Jerome Rothen is expecting the Paris Saint-Germain forward to miss four games.
Andre Villas-Boas menyatakan kebimbangannya terhadap Alvaro Gonzalez dan keluarganya selepas menerima ugutan termasuk ancaman bunuh berikutan kemenangan Marseille di Paris Saint-Germain (PSG), kelmarin.
Marseille's Alvaro Gonzalez was accused by Paris Saint-Germain's Neymar of making a racial slur in Sunday's Classique, which he denies.