Aymeric Laporte had to be taken off on a stretcher in the first half of Manchester City's commanding victory over Brighton and Hove Albion.
Sergio Aguero scored twice, with Raheem Sterling also again on target, as Manchester City climbed to second by beating Bournemouth.
With a brace against Bournemouth, Sergio Aguero took his career goals tally for club and country to 400.
Gabriel Jesus misses Manchester City's matches against Bournemouth and Brighton and Hove Albion due to a hamstring strain.
Gabriel Jesus had a late winner against Tottenham ruled out by VAR, with Manchester City players confused by the controversial call.
Tottenham were completely outplayed at the Etihad Stadium on Saturday, but their 2-2 draw shows Manchester City still have weaknesses.
Manchester City's Premier League winning streak ended with a 2-2 draw against Tottenham as a late Gabriel Jesus strike was ruled out by VAR.
Manchester City welcome Tottenham to the Etihad Stadium on Saturday - will the reigning champions make it two wins from two?
Raheem Sterling's treble and one goal apiece from Gabriel Jesus and Sergio Aguero gave Manchester City a big win over West Ham.
Sergio Aguero and Paulo Dybala scored Argentina's goals as they beat Chile to take third place in the Copa America.