After missing out on Six Nations glory, Ireland have named three uncapped players in their squad for the Autumn Nations Cup.
The Wallabies and All Blacks named their teams for Saturday's meeting in Brisbane.
Adam Hastings is set to miss the Six Nations and Gregor Townsend will also be without Finn Russell for the Autumn Nations Cup.
South Africa withdrew from this year's Rugby Championship but remain committed through to 2030 amid a restructure.
With France defeating Ireland 35-27 in Paris, England are Six Nations champions for the first time since 2017.
Captain Owen Farrell believes England's combination of youth and experience can deliver more success after their Six Nations triumph.
Ireland needed to beat France by seven points to win the Six Nations, yet England claimed the title as Andy Farrell's side lost 35-27.
Antoine Dupont and Romain Ntamack starred as France defeated Ireland 35-27 in Paris, ensuring the Six Nations title went England's way.
England secured the bonus-point win they needed to ramp up the pressure on Ireland and France in the battle for the Six Nations title.
Ben Youngs, who scored two tries for England against Italy on his 100th appearance, is already looking ahead to a bright future.