Valencia have confirmed striker Rodrigo Moreno suffered a knee ligament injury during Wednesday's LaLiga defeat to Athletic Bilbao.
Voro's first game in charge of the club – in his sixth spell as coach in total – ended in a 2-0 loss at Mestalla, with Raul Garcia's double handing Athletic all three points.
Another blow for 10th-placed Valencia came in the form of an injury to Rodrigo, with the 29-year-old now confirmed to have suffered a partial tear in the lateral collateral ligament of his right knee.
Rodrigo has struggled to find his best form this season, scoring just seven times in all competitions.