Lecce were relegated from Serie A following a 4-3 final-day defeat at home to Parma as Genoa retained their top-flight status.
Fabio Liverani guided Lecce to promotion last season, but they will make an immediate return to the second tier.
A Fabio Lucioni own goal and Gianluca Caprari's strike gave Parma a two-goal lead, but Antonin Barak and Biagio Meccariello ensured Lecce were back on level terms at the break.
They went down fighting, but Andreas Cornelius and Roberto Inglese put Parma in command again before Gianluca Lapadula pulled one back in a thriller.
Lecce would have suffered the drop with SPAL and Brescia in any case, as Genoa cruised to a 3-0 victory over Verona to finish four points above the drop zone, Antonio Sanabria helping himself to a double.
Cristian Romer added a third goal before half-time and was later sent off, while Genoa also had Francesco Cassata dismissed late on along with Verona's Sofyan Amrabat.