Paulo Dybala could be out for almost three weeks after suffering a knee injury against Sassuolo on Sunday, Juventus have confirmed.

The Argentina international was replaced by Dejan Kulusevski in the 43rd minute of Juve's 3-1 Serie A win at the Allianz Stadium.

The club confirmed on Monday he has suffered a "low-grade lesion of the medial collateral ligament" in his left knee and will be out of action for "approximately 15-20 days".

The 27-year-old looks certain to miss the Coppa Italia clash with Genoa on Wednesday, the Supercoppa Italiana against Napoli next week and Serie A games versus Inter and Bologna. He could also miss another league game against Sampdoria on January 30.

Juve's only Serie A defeat this season came when Dybala was not in the side. Their win ratio without him is 40 per cent compared to 63.6 per when he features.

When going back to the start of the 2019-20 campaign, Juve have lost as many times in the 10 league games without Dybala (four) as they have in the 44 in which he has taken part – their win percentage sliding from 72.7 to 30 in his absence.

Juve also confirmed Weston McKennie and Federico Chiesa underwent tests on Monday, which revealed neither player is suffering from a serious injury.