West Brom returned to the top of the Championship with a 2-0 victory over Luton Town after Leeds slumped to another stunning home defeat against struggling Wigan Athletic.
Leeds started their clash with third-bottom Wigan holding a two-point lead at the summit, but a Pablo Hernandez own goal was enough for Wigan to pull off a repeat of their victory at Elland Road last season.
A Donervon Daniels own goal and Semi Ajayi's header moved Albion a point clear of Leeds, while Fulham are just three points adrift of Marcelo Bielsa's men following their 3-2 defeat of Huddersfield Town.
Just six points separate the top six following wins for Brentford and Bristol City, with Nottingham Forest slipping to fourth after they went down 2-1 at Birmingham City.
Charlton Athletic's 2-1 win over fellow strugglers Barnsley moved them four points clear of the relegation zone.
Preston North End were held to a 1-1 home draw Swansea City, while it was also all square in the encounters between Sheffield Wednesday and Millwall and Middlesbrough and Blackburn Rovers.
DEJA VU AT ELLAND ROAD FOR TOOTHLESS LEEDS
Leeds mounted a storming fightback to beat Millwall in midweek and a home encounter with Wigan appeared to be a great opportunity to build on what was their first win in four league matches.
Yet Wigan inflicted a costly 2-1 defeat late in the Yorkshire club's bid for automatic promotion last year and Paul Cook's side headed back to Lancashire with three precious points again this time around.
Joe Williams' corner deflected off Hernandez and into the net just before the hour-mark and wasteful Leeds were unable to respond, slumping to a third loss in four.
BAGGIES RESPOND, FIVE-STAR BEES THUMP HULL
West Brom were beaten at Cardiff on Tuesday after losing their previous Championship encounter with Stoke City, but there was no slip-up against bottom side Luton at The Hawthorns.
Brentford had failed to score in their previous three matches in all competitions, but Said Benrahma scored a hat-trick as they thrashed Hull City 5-1 at the KC Stadium to move four points behind Leeds.
All five goals came in the first half of Fulham's 3-2 victory over Huddersfield, while Bristol City have won four in a row in the league without conceding following a 1-0 success at QPR.
CHARLTON CLAIM PRECIOUS RARE WIN
Only a second Championship win in 18 games moved Charlton above Stoke, hammered by Derby County on Friday, and Huddersfield.
Lyle Taylor and Andre Green were on target for the Addicks, leaving Barnsley seven points behind a Stoke side sitting just above the bottom three.