Rory McIlroy has been dropped for Saturday's foursomes line-up against the United States as Padraig Harrington's Europe fight to recover from a forgettable opening day at the Ryder Cup.

Team Europe face an uphill battle to retain the Ryder Cup after the USA snatched their biggest opening-day lead since 1975 as the hosts surged 6-2 ahead on Friday.

McIlroy suffered two heavy defeats at Whistling Straits, where the former world number one will watch from the sidelines on Saturday morning.

A 5 and 3 loss to Patrick Cantlay and Xander Schauffele alongside Ian Poulter in the foursomes was followed by a 4 and 3 defeat in his pairing with Shane Lowry against Tony Finau and Harris English in the afternoon four-balls.

McIlroy – a four-time major champion – has been benched for the first time in his Ryder Cup career, having featured in every session since debuting in 2010.

"He's already a leader," Harrington said of McIlroy prior to the pairings being released. "You saw him out there after a tough day. He was out following those matches and supporting his team. He is very much a leader amongst his peers.

"I couldn't have asked more from him during the year. I couldn't have asked more from him today.

"Yeah, the golf didn't go as well as he would have liked, but I'm not second-guessing him for a second in terms of his leadership and what he does for my team."

World number one Jon Rahm and fellow Spaniard Sergio Garcia will lead Europe out against USA pair Brooks Koepka and Daniel Berger.

Dustin Johnson and Collin Morikawa will clash with Englishmen Paul Casey and Tyrrell Hatton, Viktor Hovland and Bernd Wiesberger face American duo Jordan Spieth and Justin Thomas, while it is a Cantlay-Schauffele and Lee Westwood-Matthew Fitzpatrick showdown.

"I'm very comfortable again with the team I've put out tomorrow," Harrington said. "Wait and see in each of those matches whether they can create their own momentum and then bring that to the team."