Chris Eubank Jr will face Conor Benn and renew the two families' rivalry 29 years on from their fathers' second fight.
Chris Eubank twice faced Nigel Benn, beating him in their first bout in November 1990 before the pair drew the rematch three years later.
The latter meeting took place on October 9, 1993, and their sons will now take to the ring on October 8, 2022.
Benn's son Conor is still undefeated, with a 21-0 record that he will put on the line against Eubank Jr (32-2) at the O2 Arena in London.
"It's definitely a legacy fight," he said. "There was obviously a great rivalry between Eubank Sr and my dad, Nigel Benn.
"It's a fight that's even still spoken about now. It was one of the greatest British rivalries.
"So, the legacy lives on. It really is for the legacy, this fight. For me, it feels like the stars are aligned for this moment, to be honest."