Serena Williams has an Achilles strain that means her preparation for the French Open will be disrupted, starting with missing Rome.
Naomi Osaka returned to the US Open quarter-finals for the first time since winning in 2018, while Shelby Rogers won a stunning match.
Naomi Osaka was pushed before getting past Marta Kostyuk in the US Open third round.
Runner-up in 2016, Karolina Pliskova made a second-round exit at the US Open.
Naomi Osaka made a winning start at Flushing Meadows, where Karolina Pliskova triumphed and Coco Gauff was eliminated.
Two-time Wimbledon champion Petra Kvitova will not rush a decision over whether she will travel to New York for the US Open.
World number 12 Petra Kvitova would rather see grand slams cancelled than be played behind closed doors.
Limits on the movement of Czech citizens are being gradually lifted and Petra Kvitova has been allowed to resume her tennis training.
Tennis stars including Roger Federer have reacted with dismay to the news that Wimbledon has been cancelled for 2020.
Petra Kvitova was unable to add a second Qatar Open trophy to the one she won in 2018 as Aryna Sabalenka emerged victorious in the final.