Injury has been added to insult for Barcelona, who have confirmed Luis Suarez sustained a calf issue in their season-opening defeat.
Aritz Aduriz scored a stunning winning goal against Barcelona to match a feat only ever achieved by Lionel Messi in LaLiga.
Antoine Griezmann and Frenkie de Jong will make their first LaLiga appearances for Barcelona, but Philippe Coutinho is not involved.
Barcelona, Atletico Madrid and Real Madrid come into focus as we use Opta data to preview the new LaLiga season.
Ernesto Valverde indicated the Barcelona captain would miss Friday's game and Lionel Messi is not in the squad to face Athletic Bilbao.
Barcelona captain Lionel Messi is recovering from a calf injury and Ernesto Valverde suggested he will miss the trip to Athletic Bilbao.
Lionel Messi, Cristiano Ronaldo and Virgil van Dijk are up for UEFA's Player of the Year award, it was announced on Thursday.
Injured star Lionel Messi looks set to miss Barcelona's LaLiga opener against Athletic Bilbao.
Lionel Messi has won UEFA's Goal of the Season prize for the third time in five seasons, taking the award ahead of Cristiano Ronaldo.
Liverpool's Alisson, Trent Alexander-Arnold, Virgil van Dijk, Jordan Henderson and Sadio Mane are nominees for Champions League awards.