Real Madrid made light work of Valencia in Jeddah, with Isco particularly impressive in their victory.
Milan Skriniar is reportedly attracting interest from Manchester City, who want to strengthen their defence in January.
Raphael Varane ended Real Madrid's goal drought with a brace against Getafe, much to the relief of Zinedine Zidane.
Gareth Bale, Isco and Federico Valverde all start for Real Madrid against Barcelona, who made a late change to their midfield.
Rodrygo Goes, Vinicius Junior and Luka Modric all scored as Real Madrid edged past Club Brugge on Wednesday.
Real Madrid huffed their way to victory against relegation-threatened Espanyol at the Santiago Bernabeu, but Zinedine Zidane was satisfied.
Real Madrid's Luka Modric handed the Ballon d'Or trophy to Lionel Messi on Monday and then expressed his respect for the Barcelona forward.
Karim Benzema, Federico Valverde and Luka Modric were on target for Real Madrid in a game that saw Gareth Bale booed by his own supporters.
Luka Modric is focused on Real Madrid, but discussed a potential move to Serie A.
Real Madrid beat Atletico Madrid in extra time of the 2014 Champions League final and Luka Modric claimed it changed the club's mindset.