The Spurs have dealt with a litany of injuries this season, and Pau Gasol may be the next man out of the lineup.
Germany await Spain in the EuroBasket quarter-finals after the defending champions comfortably saw off Turkey in Istanbul.
Spain wrapped up their Group C campaign with a win over Hungary as Pau Gasol starred by setting a EuroBasket scoring record.
Spain are the reigning EuroBasket champions and will take some stopping this time around, having clocked up 192 points in two matches.
Spain opened their title defence with a comprehensive 99-60 Group C victory over Montenegro in Romania on Friday.
Toronto is now 1-12 in the first game of a playoff series in franchise history. Their only win came in 2001 against the 76ers.