England open their Six Nations campaign against Scotland on February 6 - but Kyle Sinckler will not be available.
Exeter are into a fifth Premiership final in succession, while Wasps will seek revenge as they bid to end a 12-year drought.
Sale Sharks can seal the final Premiership play-off place with a win after Saracens stormed back to deny Bath victory.
A bonus-point 40-3 victory over Leicester Tigers boosted Bristol's hopes of finishing in the Premiership's play-off places.
Saracens and Exeter Chiefs will go their separate ways at the end of the season, but a second-string battle was a reminder of their rivalry.
Two dominant spells saw Bristol Bears past Northampton Saints with ease in the Premiership on Tuesday.
Exeter Chiefs and Bristol Bears are the top two in the Premiership after victories on Friday.
Sale Sharks played with swagger as they crushed Bristol on Saturday in the Premiership, climbing to second place in the process.
A last-gasp try from Billy Keast gave Exeter Chiefs a dramatic late win over Bristol Bears.
There were comebacks for leaders Exeter Chiefs and Wasps in Friday's Premiership action.