Saracens eased past Northampton Saints but table-topping Exeter Chiefs had to repel a second-half rally from Sale Sharks.
Saracens' defeat on Friday left the door ajar for Exeter Chiefs, who downed Newcastle Falcons to go top of the Premiership.
Leicester Tigers limped to defeat at Saracens, meaning the victors once again sit top of the Premiership.
Eddie Jones' England have made a flying start to the Six Nations and next up is a trip to Cardiff to face Wales.
Taulupe Faletau will undergo more surgery on his right arm that will make him unavailable for Wales in the Six Nations.
Bath have announced that Taulupe Faletau will undergo further surgery on his right arm, which will make him unavailable for Wales.
Reported Northampton Saints target Jonathan Joseph is set to stay at Bath after signing an undisclosed contract extension.
Any hopes Toulouse had of snatching top spot in Pool 1 were extinguished as Leinster defeated Wasps to secure a home quarter-final.
Bath have confirmed number eight Taulupe Faletau broke his arm in his first match since recovering from the same injury.
Wales are set to have Taulupe Faletau available for the Six Nations, while Jonathan Joseph may be available for England.