Leeds Rhinos had to stand down seven players due to COVID-19 concerns on Friday but still came up with a win against Huddersfield Giants.
Greg Minikin scored a hat-trick as Hull KR stunned Super League leaders Wigan Warriors at Headingley.
Two Wakefield Trinity players returned positive coronavirus tests, forcing the game with Leeds Rhinos to be called off.
Wigan Warriors recovered from a poor start to beat Castleford Tigers, while two Leeds players scored hat-tricks in a rout of Salford.
After four positive coronavirus test results earlier in the week, Catalans Dragons have had another Super League game called off.
St Helens defeated Castleford 10-0 to briefly go top, but Wigan sit at the summit after a 28-10 triumph over Leeds.
St Helens showed just why they are defending Super League champions with an outstanding win at Leeds Rhinos, led by Regan Grace.
Huddersfield Giants led Leeds Rhinos 26-6 but lost an astonishing contest in extra time without adding another point.
Israel Folau, who was sacked by RA for homophobic social posts, refused to take a knee in solidarity with Black Lives Matter on Sunday.
Playing three Super League matches in a week could cause player injuries and a drop in quality, according to Stevie Ward.