Premiership Rugby confirmed Sale Sharks' match with Worcester Warriors had been cancelled amid a spate of coronavirus positives.
Sale Sharks can seal the final Premiership play-off place with a win after Saracens stormed back to deny Bath victory.
Positive COVID-19 tests at Sale Sharks will not prevent their crucial last game of the regular season from being played this weekend.
A dominant Sale Sharks performance was marred by an injury to Manu Tuilagi, while Northampton lost Courtney Lawes.
Saracens and Exeter Chiefs will go their separate ways at the end of the season, but a second-string battle was a reminder of their rivalry.
Leicester Tigers were thrashed by Wasps while Sale Sharks held off Saracens in Wednesday's Premiership matches.
Just under 3,000 fans returned to see Harlequins lose to Bath, while Owen Farrell saw red for a high tackle as Saracens lost against Wasps.
Sale Sharks played with swagger as they crushed Bristol on Saturday in the Premiership, climbing to second place in the process.
A last-gasp try from Billy Keast gave Exeter Chiefs a dramatic late win over Bristol Bears.
Some of Sale Sharks' South African players who did not take a knee have come in for some horrendous abuse.