Codie Taylor scored twice as 2019 Super Rugby champions the Crusaders defeated the Hurricanes 33-16.
The Rebels could not make their man advantage count as Ryan Lonergan's heroics off the bench sealed victory for the Super Rugby AU leaders.
Jona Nareki's quick feet left the Chiefs standing as the Highlanders pulled off a stunning Super Rugby Aotearoa victory on Friday.
Aaron Smith has recommitted to the All Blacks, Highlanders and Manawatu ahead of the Rugby World Cup and some major career milestones.
The Brumbies scored 35 unanswered points in the second half to clinch a record win over the beleaguered Waratahs.
Last year's Super Rugby Aotearoa runners-up, the Blues were too strong for the Hurricanes.
The Reds trailed for most of Friday's clash with the Rebels, but Alex Mafi's two tries helped them pinch victory at the death.
Hooker Codie Taylor scored the opening try of the 2021 season as holders Crusaders came out on top in Dunedin.
After Super Rugby AU and Super Rugby Aotearoa, the top clubs from Australia and New Zealand will do battle in a new competition.
South Africa withdrew from this year's Rugby Championship but remain committed through to 2030 amid a restructure.