Manchester United can go third with a win over Southampton, and unsurprisingly they are unchanged for Saints' visit.
Brazil will be without Alisson for their first World Cup qualifiers, but Neymar is back in the squad after missing their previous two games.
Spain has confirmed cases of coronavirus infection, but LaLiga chief Javier Tebas insists Sunday's Clasico is not under threat.
Olivier Giroud's future and Christian Pulisic's injury were on Frank Lampard's agenda ahead of Chelsea's clash with Burnley.
England head coach Chris Silverwood confirmed the tourists may not pick a spinner in the series opener with South Africa.
Wednesday's El Clasico will take place with a political backdrop due to pre-game protests, but Ernesto Valverde expects no Camp Nou trouble.
Lionel Messi hinted he had started to think about retirement earlier this week, but Ernesto Valverde sees no reason to worry.
Fabinho's injury could mean opportuinities for the likes of Naby Keita, Adam Lallana and Xherdan Shaqiri, says Liverpool boss Jurgen Klopp.
Antonio Conte thinks it is only a matter of time before Inter make more of an impact in Europe if they maintain their level in Serie A.
Garry Monk had some choice words about his former Birmingham City assistant Pep Clotet, leading to a retort from the Blues.