Fit-again George Ford will be among the replacements for England against Ireland, with Owen Farrell keeping his spot at number 10.
Johnny Sexton's hamstring injury has given Ross Byrne the chance to start for Ireland when they face Six Nations champions England.
Eddie Jones has given another demonstration of England's strength in despite by leaving Jack Willis out of the squad to face Ireland.
After the cancellation of the Autumn Nations Cup clash between France and Fiji, Fabien Galthie's men have been awarded the victory.
Hooker Jamie George scored half of England's six tries as the Six Nations champions coasted to a routine win over Georgia.
Italy led Scotland by seven points early in the second half, but Gregor Townsend's side were able to extend their winning run to five games.
Fly-half Nicolas Sanchez scored all 25 of Argentina's points in their win over New Zealand, having thought his Pumas career was finished.
Argentina stunned New Zealand with a famous victory in Sydney and Pablo Matera was bursting with pride over the Pumas' feat.
Head coach Ian Foster said New Zealand could have no complaints after they slumped to a first defeat against fired-up Argentina.
Nicolas Sanchez scored 25 points as the Pumas celebrated a memorable first win over the All Blacks.