Jacob Umaga and George Furbank have withdrawn, but Anthony Watson and Luke Cowan-Dickie are back in the England squad.
England produced a magnificent defensive display and Jonny May scored a first-half double as the Six Nations champions beat Ireland.
Reece Hodge had a chance to win the game for Australia against Argentina, and his missed penalty at the death left the fly-half gutted.
Reece Hodge and Nicolas Sanchez each kicked five from six penalties as Australia and Argentina fought out a draw in Newcastle.
Fiji will not play any of their group-stage matches in the Autumn Nations Cup but still intend to fulfil their final fixture.
Having both beaten New Zealand in their previous outings, Argentina and Australia will hope to claim top spot in the Tri Nations.
Fit-again George Ford will be among the replacements for England against Ireland, with Owen Farrell keeping his spot at number 10.
Johnny Sexton's hamstring injury has given Ross Byrne the chance to start for Ireland when they face Six Nations champions England.
Eddie Jones has given another demonstration of England's strength in despite by leaving Jack Willis out of the squad to face Ireland.
After the cancellation of the Autumn Nations Cup clash between France and Fiji, Fabien Galthie's men have been awarded the victory.