Novak Djokovic could not deny the remarkable Rafael Nadal, who secured yet another title in Rome on Sunday.
There is the potential for an all-American affair between teenager Amanda Anisimova and 40-year-old Venus Williams after the former won.
Reigning French Open champion Iga Swiatek dropped just 13 points as she dominated Karolina Pliskova 6-0 6-0 on Sunday.
Andy Murray will miss the French Open as he focuses on being ready for playing on grass at Queen's Club and Wimbledon.
Iga Swiatek fended off Coco Gauff in the first career meeting between the teenage WTA stars, earning a place in the Rome final.
Novak Djokovic fought off a tenacious Italian opponent and the partisan Rome crowd to reach the Internazionali d'Italia men's final.
Having sat a set and a break down heading into the resumption, Novak Djokovic demonstrated all his fighting qualities to recover in Rome.
Former French Open winner Ash Barty was a set up against Coco Gauff but retired injured from their Internazionali d'Italia quarter-final.
Roger Federer has mixed feelings about the Olympic Games happening in Tokyo this year, while Japan remains deeply affected by the pandemic.
Reigning Internazionali BNL d'Italia champion Novak Djokovic has work to do when his quarter-final with Stefanos Tsitsipas resumes.