The Portland Trail Blazers edged the Dallas Mavericks thanks to a stunning display from Damian Lillard.
Joel Embiid will sit out Philadelphia's clash against the Phoenix Suns in Orlando, Florida on Tuesday due to an ankle injury.
After key misses against the Clippers on Saturday, Damian Lillard responded with a huge performance to help beat the 76ers.
The Brooklyn Nets beat the Los Angeles Clippers to secure the east's seventh seed, while Damian Lillard inspired the Portland Trail Blazers.
Ben Simmons will leave the NBA bubble in Orlando to have surgery on his left knee, dealing a blow to the Philadelphia 76ers.
Another even team performance saw the Boston Celtics comprehensively beat the Toronto Raptors.
The Philadelphia 76ers could be without Ben Simmons for an extended period after he suffered a partial dislocation of his patella.
Brett Brown was "very curious" to know how badly Ben Simmons was injured in the Philadelphia 76ers' victory on Wednesday.
The Los Angeles Lakers struggled in a loss to the Oklahoma City Thunder in the NBA.
The Philadelphia 76ers' Ben Simmons suffered a knee injury on Wednesday.