Novak Djokovic and Dominic Thiem are both through to the last 16, but the Austrian looked to be in better shape after his triumph.
It was a good day for the vast majority of the big names in action in the men's draw at the Australian Open, as well as Nick Kyrgios.
Novak Djokovic said he had "no respect" for Nick Kyrgios and refused to reply to the Australian's response after winning at Melbourne Park.
Gael Monfils was the biggest casualty on day one of the Vienna Open, but Andrey Rublev had no such issues.
Gilles Simon sprung a surprise on Denis Shapovalov in Cologne, where Diego Schwartzman made serene progress to round three.
Andrey Rublev and Denis Shapovalov will fight it out for a place in the final of the St. Petersburg Open on Saturday.
Novak Djokovic made an imperious start to his Roland Garros title challenge as the former champion began his pursuit of more glory in Paris.
World number one Novak Djokovic will take on Rafael Nadal's conqueror Diego Schwartzman in Monday's Internazionali d'Italia final.
Rafael Nadal was chasing a 10th title on clay in Rome, but he will head to the French Open on the back of a surprise quarter-final defeat.
Fabio Fognini paid for a sloppy performance as he crashed out of the Internazionali d'Italia. Andrey Rublev and Milos Raonic also departed.