Sam James and Denny Solomona were among Sale Sharks' try-scorers as Steve Diamond's side beat London Irish to go top of the Premiership.
There was no debut victory for Bath new boy Rhys Webb as Bristol Bears continued their charged at a packed Rec.
London Irish handled challenging conditions impressively to win at Harlequins, while champions Saracens were too good for Sale Sharks.
Northampton Saints looked to be heading top of the Premiership until London Irish sprung a shock following Api Ratuniyarawa's dismissal.
Sam Hill and Gareth Steenson starred for Exeter in their win over London Irish, while Taqele Naiyaravoro was the hero for Northampton.
Munster put in a monumental effort, but Leinster's defence refused to buckle at Thomond Park.
Northampton Saints defeated Gloucester in a barnstorming contest at Franklin's Gardens, while Sale Sharks overcame Bath in the Premiership.
Bath arrived at the Madejski Stadium with no form to speak of, but Stuart Hooper's side stormed to a comprehensive win against London Irish.
London Irish battled to claim a draw at Bristol Bears despite seeing Ollie Hoskins sent off on the stroke of half-time.
Exeter Chiefs were in control at half-time, but Bristol Bears scored 20 points without reply in the second half to snatch a stunning win.