Sam Simmonds and Olly Woodburn scored doubles as Exeter Chiefs ran in eight tries to obliterate Bath 57-20, sealing their return to the top of the Premiership.
Sale moved into first place on points difference with their emphatic win over London Irish on Friday, but Exeter swiftly returned to the summit with a dominant performance of their own.
They were 36-3 up when number eight Simmonds' second try one minute into the second half was successfully converted.
Bath then touched down three times to make the scoreline more respectable but could not avoid defeat, with Woodburn and Jack Maunder increasing Exeter's margin of victory in the closing stages.
Elsewhere on Saturday, a Saracens team that included Mako Vunipola earned a 24-13 home win over struggling Leicester Tigers thanks to two Alex Lewington tries.
Controversy has surrounded Vunipola, who was stood down by England for their Six Nations match against Wales after returning from Tonga via Hong Kong amid coronavirus fears, even though he has not displayed symptoms.
Ben White ran in Leicester's only try of the match in the second half to put his side ahead, but the momentum changed when Dominic Morris crossed for Sarries just after the visitors had Telusa Veainu sent to the sin bin for a deliberate knock-on.
Wasps claimed a third straight win under Lee Blackett to move above Bath and up to fifth place as they saw off Gloucester at the Ricoh Arena.
The hosts triumphed 39-22, having scored 22 unanswered points in the first 30 minutes. Gloucester have now suffered six consecutive defeats across all competitions.