Cameron Smith was relieved to cling on for victory in the NRL Grand Final, admitting Melbourne Storm "did it the hard way" after surviving a late rally from the Penrith Panthers.

Melbourne appeared on course for a comfortable triumph at ANZ Stadium when they led 26-0 early in the second half, but ending up hanging on for a 26-20 win.

Penrith scored four tries to come charging back into a contest that saw their opponents finish with 11 men, Jahrome Hughes and Brandon Smith both sent to the sin-bin in a dramatic conclusion.

However, Melbourne survived a desperation final play from the Panthers to prevail, securing the club's fourth premiership in the NRL era.

Smith was full of praise for Penrith, not just for their late rally but also a 2020 season that saw them win 17 games in a row heading into Sunday's clash, while also spoke of his pride for a Storm squad forced to leave Victoria due to the coronavirus pandemic.

"We did it the hard way, 11 men in the end," Melbourne's captain, who scored one of his team's four tries, said in a post-game interview during which he refused to be drawn on whether he plans to prolong his career.

"Penrith were coming home with a wet sail and playing the footy that they've played all year, which has been terrific.

"As an opposition club and organisation, we've admired what Penrith have done. To win 17 in a row in this competition is a special effort, on top of what everyone has been through this year.

"If there was another couple of minutes on the clock, who knows what would have happened there. You've got to give credit to Penrith, they fought to the end.

"But I'm just proud of this football team, not just the ones that played tonight but the entire squad. We haven't been home for about five months and with the conditions that we've been under, it's a remarkable effort to be here tonight and get a victory."

A COVID-19 outbreak denied Melbourne home comforts, but Smith revealed overcoming adversity had created a bond within the group that will forever remain strong.

Justin Olam, Suliasi Vunivalu and Ryan Papenhuyzen also touched down for Craig Bellamy's side in the final, while their talismanic skipper booted 10 points.

"We've had some close-knit teams during my time with the club, but given the situation we've been here, pretty much living in each others' pockets for five months, it's something very different, something we've never experienced," Smith added.

"We grew as a unit this year and there are connections in this team now that we will have for the rest of our lives."