Antoine Griezmann will make his LaLiga debut for Barcelona against Athletic Bilbao on Friday, but Philippe Coutinho is not involved.
The France international, who joined from Atletico Madrid for €120million in the close season, starts in attack alongside Luis Suarez and Ousmane Dembele at San Mames.
There is no place in the squad for Coutinho, who continues to be linked with a move away from Barca.
The latest reports in Spain suggest the Brazil international, also said to have been offered to Paris Saint-Germain as a makeweight in a possible deal for Neymar, could be preparing to travel to Germany to finalise a loan move to Bayern Munich.
Frenkie de Jong makes his first league outing for Barca and lines up alongside Sergi Roberto and Carles Alena in midfield, while Sergio Busquets, Samuel Umtiti and Ivan Rakitic are named among the substitutes.
Lionel Messi will not feature due to a calf injury that kept the club captain out of Barca's friendly matches against Napoli in the United States last week.