Rory McIlroy and Dustin Johnson are to team up to take on Rickie Fowler and Matthew Wolff in a $3million charity skins event, which will mark the return of televised golf.
The TaylorMade Driving Relief is to take place at the Seminole Golf Club in Florida on May 17 and will raise money for the American Nurses Foundation and CDC Foundation.
A further $1m for a birdies-and-eagles pool has been pledged by Farmers Insurance to benefit Off Their Plate, which aids COVID-19 healthcare workers.
The exhibition will be the first televised golf since the coronavirus pandemic brought the 2020 season to a halt at the Players Championship in March.
A PGA Tour statement added: "The competition will follow strict CDC social distancing guidelines, local mandates and will utilise appropriate testing measures to help protect the health and safety of the golfers, production crew and others on site”. No spectators will be allowed to attend.
"It's been difficult to witness what so many are enduring over the last several weeks due to the COVID-19 pandemic," McIlroy said in a statement published on golfchannel.com.
"I hope that we can provide some respite and entertainment for those tuning in across the globe.
"Dustin and I will have a lot of fun together and our games will fit well as we push to raise funds and awareness on May 17."
McIlroy and Johnson will represent the American Nurses Foundation, while Fowler and Wolff are to play for the CDC Foundation.
The PGA Tour is scheduled to return with the Charles Schwab Challenge at the Colonial Country Club in Texas in the second week of June without fans in attendance.