LeBron James has been ruled out of the Los Angeles Lakers' clash with the Philadelphia 76ers on Thursday due to left knee soreness.

Lakers head coach Frank Vogel revealed pre-game that the 37-year-old four-time MVP had woken up with soreness and would not face the in-form 76ers, who are 28-19.

James has been in excellent scoring form lately, averaging 29.1 points, shooting 52.2 per cent from the field and 35.2 per cent beyond the arc across the season.

The veteran superstar has scored 25 points or more in each of the Lakers' past 18 games, dating back to mid-December. Only once – in 21 games for the Cleveland Cavaliers in 2008 – has he enjoyed a longer such streak.

James has averaged an astonishing 32.5 points over this period, although the Lakers have gone 8-10.

"He’s out tonight," Vogel said of his star man on Thursday. "Just woke up with some soreness that was enough to hold him out. He’ll be day-to-day."

James had only just reunited with Anthony Davis on the court, with the All-Star forward returning from an MCL sprain in Tuesday's 106-96 win over the Brooklyn Nets.

Besides scoring 29.1 points per game, up on his career average of 27.1, James is averaging 6.3 assists and 7.7 rebounds this season.