Mercedes have never looked back since dethroning Red Bull to take the constructors' title in 2014, going on to make history.
Sebastian Vettel paid the price for a poor start from pole as Valtteri Bottas claimed his third win of the season at Suzuka.
Ferrari had a forgettable first lap, with a frustrated Sebastian Vettel slow off the line and Charles Leclerc hitting Max Verstappen.
Ferrari's Sebastian Vettel topped the timesheets in qualifying for Sunday's race.
Eddie Irvine believes Charles Leclerc is Ferrari's best driver and feels not favouring the youngster is costing the Formula One team.
Mercedes could win the constructors' championship at a Japanese Grand Prix that has already been impacted by Typhoon Hagibis.
Ferrari's team tactics have dominated conversation in the past two races, but Charles Leclerc says they are not "a huge deal".
With Typhoon Hagibis having already forced the cancellation of two Rugby World Cup matches, the Japanese Grand Prix is now under threat.
Ferrari do not have fond memories of racing at Suzuka in recent years, with Mercedes dominating.
Ferrari have won three of the four races since the mid-season break, leading to action from Mercedes ahead of this weekend's race in Suzuka.