River Plate progressed to the Copa Libertadores knockout stage after a win at Palestino.
Boca Juniors scored four goals against Jorge Wilstermann on Wednesday, after Cruzeiro's Fred celebrated a first-half hat-trick.
Marco Ruben led Athletico Paranaense to an impressive win over Boca Juniors in the Copa Libertadores.
Boca Juniors and Palmeiras both won 3-0 in the Copa Libertadores on Tuesday.
Last season's runners-up Boca Juniors were held by Bolivian hosts Jorge Wilstermann in Group G on Tuesday.
We assess the leading candidates for glory and the potential stars ahead of the start of the 2019 Copa Libertadores.
After the sale of Leandro Paredes to Paris Saint-Germain, Russian side Zenit have completed a deal to sign Wilmar Barrios.
After unsuccessful loans in Serie A, Benfica defender Lisandro Lopez has returned to Argentina with Boca Juniors.
Leonardo Balerdi has swapped Boca Juniors for Borussia Dortmund after signing a long-term deal at Signal Iduna Park.
Defender Leonardo Balerdi is set to complete a move to Borussia Dortmund, according to Boca Juniors president Daniel Angelici.