Michy Batshuayi will start Chelsea's trip to Hull City on Saturday and boss Frank Lampard is eager for the striker to show more consistency.
Xherdan Shaqiri has been plagued by injuries this season and Liverpool boss Jurgen Klopp shares the midfielder's frustrations.
Tottenham head coach Jose Mourinho lamented the timing of his side's upcoming break.
Liverpool star Virgil van Dijk warned his team there was still a long way to go in the Premier League.
Liverpool boss Jurgen Klopp insists they have not won the Premier League yet, saying: "We couldn't care less about these sorts of things."
Kepa Arrizabalaga has attracted criticism in recent weeks and Chelsea boss Frank Lampard admitted the goalkeeper "needs to improve".
A glute problem saw Jamie Vardy withdrawn from Leicester City's Premier League match with West Ham and he will be absent against Brentford.
Tammy Abraham has avoided a serious ankle injury but Frank Lampard is still keen to bolster Chelsea's attacking options this month.
Arsenal have been linked with a number of transfers in and out of the club, but Mikel Arteta does not see Pierre-Emerick Aubameyang leaving.
Sadio Mane will likely miss the FA Cup trip to Shrewsbury Town, but Jurgen Klopp seems confident Takumi Minamino can fill in.