A calf injury sustained in practice this month has curtailed Timea Bacsinszky's hopes of playing at the French Open.
Top seed Dominic Thiem won twice on Friday to reach the final of the Lyon Open, where he will face Frenchman Gilles Simon.
With the French Open looming on the horizon, Ashleigh Barty took the "tough decision" to pull out of the Internationaux de Strasbourg.
Serena Williams is something of an outsider at Roland Garros given her lack of match action. However, the draw has been kind to her.
Reigning French Open champion Jelena Ostapenko has admitted winning at Roland Garros led to changes on and off the court.
Jelena Ostapenko's unlikely French Open success of last year has several players hoping for similar feats in 2018.
After making her comeback from a career-threatening injury last year, Petra Kvitova is expected to be in the mix at Roland Garros.
Asked if French Open wins were "more beautiful" when Roger Federer was in the field, a smiling Rafael Nadal said: "Exactly the same."
Simona Halep is pleased the likes of Serena Williams, Victoria Azarenka and Maria Sharapova are competing at this year's French Open.
Found guilty of match-fixing offences, Argentinian Nicolas Kicker has been suspended.