Chile overcame Ecuador at the Copa America to move into the quarter-finals from Group C.
Fifteen-time champions Uruguay begin their latest bid for Copa America glory with a showdown against out-of-form Ecuador in Belo Horizonte.
Seeking their first title after two previous finals, Tigres UANL defeated Santos Laguna 5-3 on aggregate.
Tigres UANL closed in on the CONCACAF Champions League final after beating Santos Laguna 3-0.
Enner Valencia helped Tigres UANL beat Houston Dynamo in the first leg of their CONCACAF Champions League quarter-final.
Tigres UANL reached the CONCACAF Champions League quarter-finals thanks to hat-trick hero Enner Valencia.