The draw for the Copa Libertadores round of 16 took place in Paraguay on Monday.
Santiago Arzamendia scored in Tuesday's 1-1 draw away to Uruguayan hosts Nacional as Cerro Porteno topped Group E on goal difference.
River Plate progressed to the Copa Libertadores knockout stage after a win at Palestino.
After three consecutive draws, River Plate defeated lowly Peruvian side Alianza Lima 3-0 on Thursday to move up to second in the group.
Nicolas De La Cruz's spectacular free-kick helped River Plate earn a draw at Internacional in the Copa Libertadores.
Colombia are set to be without Juan Fernando Quintero at the Copa America after he suffered a ruptured cruciate ligament.
Playing behind closed doors at the Monumental, River Plate were held by Palestino in the Copa Libertadores.
Defending champions River Plate snatched a last-gasp draw at Alianza Lima on Wednesday.
We assess the leading candidates for glory and the potential stars ahead of the start of the 2019 Copa Libertadores.
MLS Cup champion Atlanta United have sealed the signing of River Plate midfielder Gonzalo "Pity" Martinez.