JJ Williams wrote off Wales' World Cup chances after Dan Biggar stepped into the number 10 shirt, but he responded with a fine display.
Dan Biggar, James Davies and Jake Ball come into the Wales side as they eye revenge against England in Cardiff.
Wales head coach Warren Gatland had injury worries to contend with following a 33-19 World Cup warm-up defeat to England at Twickenham.
Warren Gatland is set to take over the Chiefs on a four-year deal that will allow him to coach the British and Irish Lions in 2021.
The Chiefs announced the appointment of Warren Gatland as their head coach on a four-year deal.
After initially ruling out leading the Lions again, Warren Gatland said he could not refuse the chance to gain revenge in South Africa.
Departing Wales head coach Warren Gatland will take charge of the British and Irish Lions for a third time.
Warren Gatland will make a swift return to Wales to take on Wayne Pivac's side with the Barbarians in November.
Wales coach Shaun Edwards has urged focus on this year's World Cup and not his next career move following comments by Wayne Pivac.
Scotland full-back Stuart Hogg has welcomed reports that Warren Gatland will coach the Lions in South Africa in two years' time.