Daniele De Rossi is a target for Boca Juniors, but the free agent is reportedly set to sign for Los Angeles FC in MLS.
The draw for the Copa Libertadores round of 16 took place in Paraguay on Monday.
The pots are set for the last 16, with the draw scheduled to take place in Paraguay on Monday.
River Plate progressed to the Copa Libertadores knockout stage after a win at Palestino.
Boca Juniors scored four goals against Jorge Wilstermann on Wednesday, after Cruzeiro's Fred celebrated a first-half hat-trick.
Marco Ruben led Athletico Paranaense to an impressive win over Boca Juniors in the Copa Libertadores.
Boca Juniors and Palmeiras both won 3-0 in the Copa Libertadores on Tuesday.
Last season's runners-up Boca Juniors were held by Bolivian hosts Jorge Wilstermann in Group G on Tuesday.
We assess the leading candidates for glory and the potential stars ahead of the start of the 2019 Copa Libertadores.
After the sale of Leandro Paredes to Paris Saint-Germain, Russian side Zenit have completed a deal to sign Wilmar Barrios.