Dallas claimed a 3-2 victory over Tauro but they failed to reach the quarter-finals on away goals – the tie ending 3-3 on aggregate.
Tigres UANL reached the CONCACAF Champions League quarter-finals as Enner Valencia starred.
Guadalajara drew first blood in the Dominican Republic Thursday thanks to Jesus Sanchez and Jose Macias.
Cecilio Dominguez and Mateus Uribe scored braces as America thrashed Deportivo Saprissa.
Sebastian Giovinco scored and provided an assist as Toronto beat Colorado Rapids in the CONCACAF Champions League.