Even without the suspended Zlatan Ibrahimovic, LA Galaxy still managed to beat the San Jose Earthquakes on Friday.
Nice have been linked with appointing Patrick Vieira as a replacement for Lucien Favre, but the Frenchman has denied the reports.
David Villa, 36, was the hero on Saturday as he helped end New York City's two-match winless streak.
Atlanta United made it eight wins from 11 games in MLS thanks to a victory over Orlando City.
New York Red Bulls used a blistering start to claim bragging rights, two goals inside the opening four minutes inspiring a crushing victory.
David Villa became the sixth active player to score 400 career goals but the 36-year-old forward wants more.
David Villa celebrated a memorable milestone, while LAFC's first match at their new stadium ended in dramatic fashion.
Patrick Vieira was asked about Arsenal and Arsene Wenger but the New York City head coach was only keen to dissect Sunday's loss in MLS.
New York City lost to Portland Timbers – their first defeat of the 2018 MLS season – while Seattle Sounders beat Minnesota United.
Arsene Wenger's decision to leave Arsenal has seen Patrick Vieira named as a possible replacement, but the coach claims he is happy in MLS.