Bordeaux-Begles, nudged into second on Saturday, could not return to the Top 14 summit at Toulouse.
Top 14 front-runners Lyon won again, while La Rochelle's Arthur Retiere grabbed a hat-trick and Brive left it late.
Stade Francais came into the Clasico sitting bottom of the Top 14, yet they pulled off a thrilling win in Paris as Toulouse wilted.
He may have been granted an early release by Toulon, but Rhys Webb will not play for them again if owner Bernard Lemaitre has his way.
High-flying pair Lyon and Bordeaux Begles celebrated contrasting victories in Top 14 action on Saturday.
Having been granted an early release from his Toulon contract, Rhys Webb has agreed a return to Ospreys in 2020.
A move to the Ospreys or the Dragons is reportedly on the cards for Rhys Webb after Toulon agreed to release him from his contract early.
Bordeaux-Begles are back at the top of the Top 14 and increased their advantage over Toulon and Toulouse.
There were wins for Lyon and Racing 92 in the Top 14 as Bordeaux-Begles were usurped at the summit.
Toulouse safeguarded the future of their France full-back Thomas Ramos as the Top 14 club entered into the festive spirit on Christmas Eve.