A 1-1 draw with lowly Wigan Athletic denied West Brom the chance to climb back above Leeds United at the top of the Championship.
Bristol City's 2-0 win at Fulham put the Robins right in the promotion picture, while leaders Leeds United beat Huddersfield Town.
Manchester City have a favourable draw in the FA Cup third round, but there are difficult trips for Everton and Manchester United.
Brentford scored seven times in a rampant win over Luton on a day when Leeds went top of the Championship with West Brom not playing.
A comfortable home win over Bristol City moved West Brom back into top spot, while Garry Monk avoided defeat against his former side.
Jake Livermore was on target as West Brom saw off Hull City, while there were wins for Preston North End and Leeds United.
Leeds United picked up a first win in three at home to QPR, sending them above Swansea City to the Championship summit.
Brentford picked up a third successive Championship win by seeing off QPR 3-1 on Monday, with Ollie Watkins scoring twice.
The Championship's top two, West Brom and Leeds United, were held on Tuesday, while Sheffield Wednesday moved up to third.
West Brom stayed ahead of Leeds United at the top of the Championship, where plenty of the struggling sides picked up vital points.