The mercurial Finn Russell has been punished for a breach of team protocol just nine days before Scotland's first Six Nations game.
Johnny Sexton expects to lead Ireland against Scotland in Dublin and Jordan Larmour is expected to be in contention.
Andy Farrell has opted to add more depth at centre to Ireland's Six Nations squad in the form of Stuart McCloskey.
West Indies forced a drawn Twenty20 series against Ireland in the third and final match.
No result was declared after the game was called off – Ireland boasting a 1-0 lead in the three-game series.
Ireland sealed a nail-biting four-run win over West Indies after Paul Stirling's stunning 95 laid the platform for a famous triumph.
Andy Farrell has called up five uncapped players into his first Ireland squad, with Johnny Sexton confirmed as the team's captain.
West Indies completed an ODI whitewash of Ireland thanks to a century from Evin Lewis in Grenada.
Sheldon Cottrell's six off the second last ball of the innings saw West Indies edge Ireland.
Joey Carbery has suffered another injury blow and will play no part in Ireland's bid to regain the Six Nations title.