EWE Baskets and Banvit could not be separated in their first leg, while PAOK and AEK only have small leads to defend.
CEZ Nymburk held a 31-point advantage in the second leg, but were still unable to avoid a Basketball Champions League exit.
After failing to make an impact at Lazio, Moritz Leitner has sealed a return to the Bundesliga with Augsburg.
The group stage of the Basketball Champions League is now complete, with four more teams sealing their places in the last 16.
CSM CSU Oradea held their nerve to secure an over-time victory over Kataja Basket in the Basketball Champions League, Martin Zeno starring.
EWE Baskets stayed on course for a top-two place in Group C of the Basketball Champions League, with Chris Kramer setting a new record.
An excellent performance in the final frame from Jerai Grant ensured Neptunas Klaipeda came from behind to beat PAOK and go 5-0.
Besiktas and Tenerife maintained their 100 per cent records in the Basketball Champions League with away wins on Tuesday.
AEK Athens comfortably overcame Proximus Spirou 80-58 to move to 2-0, while Neptunas Klaipeda did the same by thrashing Varese 94-60.
The inaugural Basketball Champions League started on Tuesday and Tenerife were among the winners.