Argentina have made five changes for their meeting with South Africa as Benjamin Urdapilleta prepares for an international return.
Argentina will be unable to use Lionel Messi before November after CONMEBOL banned him for his "corruption" comments at the Copa America.
Having reached the semi-finals of the Copa America, Argentina have given Lionel Scaloni their backing for the 2022 World Cup qualifiers.
Saturday's 16-10 win over Argentina saw Australia veteran Will Genia play at the Suncorp Stadium for the last time.
Australia were comfortable winners over Argentina in Brisbane, with all but five of the hosts' points coming from Christian Lealiifano.
James O'Connor has already impressed on his return to Australia training and Michael Hooper is keen to see him deliver on the pitch, too.
Australia are welcoming back Christian Lealiifano and James O'Connor for their clash against Argentina.
CONMEBOL confirmed a ban and fine for Lionel Messi after his red card for Argentina against Chile.
Will Genia believes James O'Connor will grasp his chance if a six-year Wallabies exile comes to an end when Australia face Argentina.