Newcastle United moved seven points clear of the drop by beating Burnley, but Rafael Benitez is not prepared to consider his team safe.
A 2-1 home win over title-chasing Tottenham moved Burnley further clear of the bottom three, to the delight of manager Sean Dyche.
Mike Dean was confronted by Mauricio Pochettino after Tottenham's defeat at Burnley, with Hugo Lloris also critical of the referee.
Referee Mike Dean was confronted by a furious Mauricio Pochettino after Tottenham went down 2-1 in the Premier League away to Burnley.
Fit-again striker Harry Kane scored on his return to the Tottenham team, but they lost 2-1 at Burnley thanks to a late Ashley Barnes goal.
Tom Heaton made five saves to help Burnley beat Brighton 3-1 and Sean Dyche said his performance was key to the victory.
Chris Wood took his Premier League goal tally to six for the season as Burnley beat Brighton 3-1 to move out of the relegation zone.
Burnley were denied what looked a blatant penalty – but did score from the spot late on – in their 1-1 draw against Southampton.
Burnley were minutes from a famous win at Old Trafford and manager Sean Dyche was not too pleased with the officials' role in the 2-2 draw.
Ole Gunnar Solskjaer has impressed Sean Dyche with his early work at Manchester United, turning the season around with eight straight wins.