Warren Gatland challenged Wales to "step it up" as he named Dan Biggar as one of three changes to his starting line-up for the World Cup warm-up match against England on Saturday.
Wales missed the chance to replace New Zealand at the top of the rankings when they were beaten 33-19 by an experimental England side at Twickenham last weekend.
Gareth Anscombe suffered a knee injury which will keep him out of the World Cup in Japan as Eddie Jones' men ended the Grand Slam winners' 14-match winning run.
Biggar comes in at fly-half to replace Anscombe, while flanker James Davies and lock Jake Ball come in for the injured Adam Beard and Justin Tipuric in Cardiff.
Fit-again flanker Josh Navidi was named among the replacements, but scrum-half Tomos Williams (shoulder) remains sidelined.
Wales head coach Gatland said: "We were disappointed to get the loss last weekend, so it is important we step it up on Saturday and put in a big display in front of a packed Principality Stadium.
"The squad are looking forward to getting back out there, taking another step towards the Rugby World Cup and putting in a big performance."
Wales team to face England on Saturday: Liam Williams, George North, Jonathan Davies, Hadleigh Parkes, Josh Adams, Dan Biggar, Gareth Davies; Nicky Smith, Ken Owens, Tomas Francis, Jake Ball, Alun Wyn Jones (captain), Aaron Wainwright, James Davies, Ross Moriarty.
Replacements: Elliot Dee, Wyn Jones, Dillon Lewis, Aaron Shingler, Josh Navidi, Aled Davies, Jarrod Evans, Owen Watkin.