Pablo Sarabia's late stunner lifted Sevilla to a 3-2 success at Leganes, their first away win in LaLiga for 17 months.
With all of LaLiga's top four in action on Saturday, breaking their away-day blues was crucial for the Andalusians and Franco Vazquez's header in the 25th minute had them on their way.
Samir Nasri doubled the lead shortly before the hour, but Jorge Sampaoli's side were stunned by two goals in the space of three minutes from the newly promoted side.
Timor and Alexander Szymanowski struck to turn the tide, but Sevilla hung on before Sarabia had the final say.
Drifting in from the left flank, Sarabia found the top-right corner with a curled right-foot effort, sending the small pocket of travelling fans delirious.
Temporarily top after their first away win in 23 in the league, Real Madrid and Atletico Madrid can move back ahead of Sevilla in later games versus Real Betis and Granada.