Ansu Fati is set for only his fourth LaLiga start after being given the nod to line up against Granada in new coach Quique Setien's first match in charge.

Setien was appointed on Monday following the sacking of Ernesto Valverde, though he has resisted any urge to make wholesale changes.

Barca's last outing saw them lose 3-2 to Atletico Madrid in the Supercopa de Espana semi-final, with Lionel Messi, Antoine Griezmann and Luis Suarez leading the line.

But since then Suarez has been ruled out for most of the season after having knee surgery, resulting in a rethink in attack.

The one to benefit from Suarez's absence is 17-year-old Fati, who broke into the first-team squad at the start of the season.

Marc-Andre ter Stegen returns in goal following a spell out with a knee injury, while the much-maligned Ivan Rakitic takes the place of the suspended Frenkie de Jong in midfield.

Setien's arrival was seen as a positive for the club's promising youngsters, with the likes of Riqui Puig – who hardly had a look-in under Valverde – brought to train with the senior side straight away.

Puig, 20, is among the substitutes at Camp Nou, as is fellow La Masia product Carles Perez.