A stunning home record in the Champions League is on the line for Juventus on matchday two, with the Serie A giants facing Young Boys without Cristiano Ronaldo.
The former Real Madrid superstar is serving a suspension for the visit of the Swiss side after he was controversially sent off two weeks ago in an away win against Valencia.
Another of Ronaldo's former clubs, Manchester United, will seek to put poor domestic form behind them in their contest with Valencia, while Premier League rivals Manchester City are seeking to bounce back from defeat to Lyon when they travel to Hoffenheim.
German giants Bayern Munich are among the other top sides in Champions League action on Tuesday and here we assess the eight ties with the use of Opta numbers.
Bayern Munich v Ajax
24 – Bayern have won 24 of their last 25 home games in the Champions League - their only loss coming against Manchester City, who beat them 3-2 in December 2013.
10 – Ajax have played 10 away games in the Champions League since their last win, which came in October 2011 against Croatian side Dinamo Zagreb.
AEK Athens v Benfica
13 – Benfica are on a run of four straight away losses in the Champions League, and have not been beaten in five consecutive away games in the competition's history. They have not scored a single goal in that sequence, but have conceded 13 times.
0 – AEK Athens were the only team that failed to land a single shot on target on matchday one, when they lost 3-0 away to Ajax.
Hoffenheim v Manchester City
1 – Pep Guardiola has lost five of his last six games in the Champions League, winning the other, with those defeats as many as the former Barcelona and Bayern coach lost in his previous 28 combined in the competition.
10 – This will be Hoffenheim's 10th European match. Their record so far stands at one win - against Istanbul Basaksehir - three draws and five defeats.
Lyon v Shakhtar Donetsk
12 – Of the 17 most recent goals scored by Shakhtar Donetsk in the Champions League, 15 have been scored by South Americans - 12 of them coming from Brazilians.
6 – Lyon have only won one of their last eight home games in the Champions League and the Ligue 1 side have failed to score in six of those matches.
